Latest High Performance Computing Jobs

Spotlight

ML Runtime Engineer (Mid-Level and Senior)

This role involves developing and optimizing the runtime stack for AI accelerators, focusing on integrating with open-source ML frameworks like PyTorch and vLLM. The engineer will work closely with hardware and software teams using a co-design approach to enable high-performance inference for large language models. Key responsibilities include building a high-performance runtime in Rust and supporting inference server integrations.

Fractile London, United Kingdom

Hybrid Permanent

Spotlight

Senior Machine Learning Scientist

This role involves developing and deploying custom machine learning and LLM-powered systems for customer feedback analysis, including fine-tuning, retrieval, summarisation, and agentic workflows. The scientist will lead experimentation, evaluation, and productionisation of models while mentoring team members and integrating cutting-edge AI research into real-world applications.

Chattermill London, United Kingdom

Remote Permanent

High Performance Computer Scientist /HPC Developer

This role involves designing and optimizing large-scale high-performance computing (HPC) systems, focusing on infrastructure reliability, computational efficiency, and performance at scale. You'll work closely with engineers and researchers to solve complex technical challenges in distributed and parallel computing environments, using advanced profiling, benchmarking, and automation techniques.

IT Graduate Recruitment London, United Kingdom £50,000 pa

Hybrid Permanent

Senior HPC Performance Engineer

As a Senior HPC Performance Engineer, you will conduct in-depth performance analysis on large multi-GPU and multi-node clusters, evaluate proof-of-concepts, and triage performance issues. You will collaborate with a dynamic team across multiple time zones to advance the state of the art in GPU communication libraries and HPC applications.

NVIDIA £221,250 – £507,000 pa

Remote Permanent

Senior HPC Performance Engineer

As a member of our team in NVIDIA's NVHPC compilers & tools group, you will analyze and run High Performance Computing (HPC) applications on HPC servers and systems to gain insight into the performance characteristics of these applications. The applications...

NVIDIA

Anthropic Fellows Program, ML Systems & Performance

Fellows in the ML Systems & Performance workstream will conduct full-time research for 4 months, focusing on empirical projects aligned with Anthropic's research priorities. They will receive direct mentorship, access to shared workspaces, and a weekly stipend, with the goal of producing public outputs such as research papers.

Anthropic United Kingdom

Hybrid Internship

Senior Solutions Architect, WWPS Global Defence Partners

This role involves leading technical strategy and solution architecture for defence-sector partners adopting AWS cloud technologies. The Senior Solutions Architect will define modernization roadmaps, design secure and scalable AWS-native systems, and act as a trusted advisor on AI/ML, HPC, and data platforms. The position emphasizes strategic engagement with systems integrators and executive stakeholders in mission-critical environments.

Amazon London, United Kingdom

Hybrid Permanent Clearance Required

Software Engineer, GPU Infrastructure- ChatGPT Engineering

Design and operate software systems managing large-scale GPU clusters that power ChatGPT inference workloads. Build automation, observability, and intelligent tooling to improve fleet reliability, efficiency, and scalability. Collaborate with infrastructure, research, and product teams to optimize compute utilization and drive operational excellence across distributed systems.

OpenAI London, United Kingdom

Hybrid Permanent

Data Science - Assistant Manager

This role involves leading the technical delivery of data science and machine learning projects, building and optimizing models, and working in cloud and high-performance computing environments. You will also support and mentor a small team while staying current with emerging trends in GenAI and advanced analytics.

eFinancialCareers London, United Kingdom £60,000 – £75,000 pa

Hybrid Permanent Clearance Required

Junior Software Engineer - Imaging Systems

Develop software for advanced imaging systems involving high-speed data processing and hardware/software integration. Work within a multidisciplinary R&D team to build and optimise backend systems, drivers, and data acquisition tools. Focus on performance-critical applications in scientific and industrial environments.

Marcus Webb Associates Limited Hollington, East Sussex, East Sussex, TN37 7BA, United Kingdom £35,000 – £40,000 pa

On-site Permanent

Staff Machine Learning Software Engineer, Research

This role involves leading machine learning engineering efforts within a research context, focusing on transforming experimental models into scalable, production-grade systems for physics-informed AI simulations. The engineer will work closely with research scientists to design and optimise distributed training architectures, build foundation models, and deliver robust ML solutions for complex engineering problems. A strong emphasis is placed on mentorship, technical leadership, and translating cutting-edge research into reusable software tools and products.

PhysicsX London, United Kingdom

On-site Permanent

Machine Learning Software Engineer, Research

This role involves working closely with research scientists and simulation engineers to build and optimize machine learning models for real-world physics and engineering problems. You will design, implement, and scale models using advanced techniques like distributed training and federated learning, while also mentoring colleagues and translating research into reusable libraries and products.

PhysicsX London, United Kingdom

On-site Permanent

Data Scientist - Defence & Security

This role involves working on cutting-edge machine learning and GenAI solutions, deploying LLMs and ML models in secure government and defence environments. You will lead technical delivery, design and optimise pipelines, and mentor junior engineers within a collaborative team.

eFinancialCareers London, United Kingdom £75,000 pa

On-site Permanent Clearance Required

Software Engineer, Platform Systems

About the TeamThe Platform Systems team at OpenAI operates at the intersection of cutting-edge AI and large-scale distributed systems. We build the engineering and research infrastructure required to train OpenAI’s flagship models on some of the world’s largest, custom-built supercomputers.Our...

OpenAI London, United Kingdom

Permanent

Senior Data Scientist

As a Senior Data Scientist, you will lead the delivery of advanced data science capabilities, working on innovative projects to help customers unlock value from complex datasets. You will mentor colleagues, shape the future of the data science team, and collaborate closely with a highly skilled team of Data Scientists, Software Engineers, and Technical Specialists.

MASS Little Paxton, Cambridgeshire, United Kingdom £45,000 – £65,000 pa

On-site Permanent Clearance Required

Snr/Principal Machine Learning Scientist – Generative Modelling

This role involves designing and implementing generative models to understand and control cellular decision-making, using cutting-edge multiomic and interventional datasets. You will collaborate with experimental teams to validate computational hypotheses and contribute to high-impact publications, pushing the boundaries of generative modelling in complex biological systems.

Relation Therapeutics London, United Kingdom

On-site Permanent

Data Scientist – Computational Genomics, 12-month

This role involves applying and developing machine learning and statistical models to analyse large-scale genomics, transcriptomics, and multi-omics datasets for target identification and validation in drug discovery. The data scientist will work at the intersection of genetics and machine learning, integrating human genetics data with functional omics to uncover disease mechanisms. Collaboration with experimental and computational teams is central to validating hypotheses and guiding therapeutic development.

Relation Therapeutics London, United Kingdom

On-site Permanent