AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10(TM), an industry-leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.Our vision: Pioneering science to create transformative molecular medicines.Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.Our principles:* Advance innovative science by pushing boundaries.* Bring transformative therapeutics to patients in need.* Provide an environment for employees to reach their fullest potential.Our values:* Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.* Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.* Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.* Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.* Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.Position SummaryThis internship provides an opportunity for a highly motivated student to gain hands-on experience applying machine learning to real biological data within a gene therapy research environment. The intern will work within the Bioinformatics and AI/Machine Learning team to integrate a next-generation machine learning model for enhancer prediction into AskBio proprietary bioinformatics platform, PromPT(R).The role will focus on building an end-to-end, user-facing ML pipeline, including data ingestion, model integration, visualisation of results, and downstream biological analysis, in close collaboration with bioinformaticians and experimental scientists. The intern will be supported through structured mentoring and regular feedback and will deliver a final presentation and live demonstration of the integrated pipeline and its applications.The intern will report to the Senior Director, Bioinformatics and AI/Machine Learning and will be based in the Edinburgh office.Job Responsibilities* Support the integration of a next-generation machine learning model for enhancer prediction into an existing bioinformatics platform* Learn how machine learning models are applied to biological sequence data in a gene therapy context* Review and understand existing bioinformatics pipelines within the PromPT(R) platform* Partner with bioinformaticians, ML and experimental scientists to gather user requirements and feedback* Assist in developing a simple user interface for model input and configuration* Develop output visualisations and summary analyses to support biological interpretation of model results* Participate in code reviews, documentation, and best-practice software development workflows* Assist in testing, validation, and performance assessment of the integrated pipeline* Communicate progress clearly through regular updates and discussions with the project team* Collect and analyse feedback from users to refine pipeline functionality and usability* Present a final demonstration of the integrated ML pipeline and its applications at the end of the internshipMinimum Requirements* Must be pursuing a Doctorate degree in Informatics, Bioinformatics, Data or Computer Science, AI or Machine Learning, or a related field* Must have completed their first year at the time of application* Coursework or academic experience in one or more of the following: bioinformatics, machine learning, data science, or computational biology* Basic programming experience in Python or a similar scientific programming language* Familiarity with fundamental concepts in machine learning or statistical data analysis* Interest in applying computational methods to biological or genomic data* Strong analytical and problem-solving skills* Ability to communicate technical ideas clearly to both technical and non-technical audiences* Organised, curious, and eager to learn in a collaborative research environment* Available to work full-time, on-site in the Edinburgh office, during the summer internship periodPreferred Education, Experience and Skills* Prior research, internship, or project experience in bioinformatics, machine learning, or data science* Exposure to biological sequence data (e.g. DNA, RNA, or genomic datasets)* Familiarity with Linux or command-line environments* Experience with data visualisation libraries or tools* Awareness of software development best practices, such as version control (e.g. Git)* Interest in gene therapy, genomics, or computational biology research*AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at .*Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.
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