Senior Bioinformatician

Hlx Life Sciences
Oxford
1 month ago
Applications closed

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About the Role:

Reporting to the Lead Bioinformatician, you will have a unique and exciting opportunity to contribute to the development, evaluation, and deployment of groundbreaking bioinformatic solutions within a real-world context. We are on the lookout for exceptional talent and someone who embodies our passion, has the technical capability and sees the vast potential for global application of our products.


You'll engage closely with our partners at the University of Oxford, demonstrating a mission-driven attitude and adaptability to fulfil our collective objectives. Your contributions will not only be valued but encouraged, as we seek your input on enhancing our offerings, platform, and operational practices. This role promises an opportunity to make a real difference in the world though bioinformatic and cloud-based analysis for patient, hospital and public health benefit.


Responsibilities:

  • Develop code, implement and evaluate computational/bioinformatic methods and tools to support research and development in infectious disease genomics including AMR determination, and outbreak and relatedness information.
  • Creating analysis pipelines and appraise and validating various tools’ performances.
  • Understand various sequencing devices and data types as well have a good enough understanding of upstream laboratory processes.
  • Be familiar with current genomic repositories such as ENA, GenBank, GISAID etc.
  • Collaborate with cross-functional teams including academics, clinicians, computer scientists, biostaticians, and biologist to develop and implement data-driven strategies.
  • Stay abreast on the latest developments in infectious diseases, bioinformatics and computational biology.
  • Be innovative and take initiate to introduce new ideas and approaches.
  • Setting performance goals and providing regular feedback.




Required Skills:

  • A PhD qualification in bioinformatics, computational biology, microbiology, mathematics, genetic epidemiology, genomics, or equivalent.
  • Experience in infectious disease genomic analysis, epidemiology, and surveillance.
  • Having a scientific understanding of infectious disease genomics.
  • Strong programming skills in languages such as Bash, Python, R, Nextflow, Docker, etc.
  • Expertise in standard bioinformatics workflows and best practices for processing microbial genomic data.
  • Expertise in data structures for next-generation sequencing data, including transformations and output formats for efficient processing and analyses.
  • 3-5+ years of experience in bioinformatics and computational biology and an established or upcoming bioinformatic publication history.
  • Experience with large-scale genetic data analysis using bioinformatics tools and pipelines.
  • Proven leadership and management skills and excellent communication skills.
  • Ability to work effectively in a high-growth, fast-paced, dynamic environment.


Preferred Skills:

  • Experience working with cloud computing.
  • Experience with regulatory guidelines and systems e.g. FDA, CE, UKCA, EUCAST.
  • Familiarity with machine learning and data visualization techniques.
  • Experience working in a biotech or pharma industry setting.
  • A track record of launching an academic product in the commercial market.
  • Experience with biostatistics and modelling for infectious diseases.

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