Principal Scientist

Disability Solutions
Stevenage
1 month ago
Applications closed

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Principal Data Scientist

Principal Data Scientist

Site Name:UK - Hertfordshire - Stevenage
Posted Date:Mar 21 2025

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpageLife at GSK | GSK

We are looking for a highly motivated scientist with experience in onco-immunology and cellular biology and flow cytometry to join the Oncology Translational Research team within GSK Oncology TA.

The Oncology Translational Research team will partner with Oncology TA team members to increase clinical translatability and to contribute to preclinical development programs within GSK Oncology TA. The successful candidate will work as part of a team that, by exploiting allogenic/autologous patient-derived PBMC alone or in combination with patient-derived organoids, is analyzing downstream immune response, developing, and implementing cutting-edge cellular, genomic and molecular techniques with a multimodality analytic approach, plus machine learning models to improve cancer patient risk stratification as well as to predict future targeted and/or immuno-therapy susceptibilities.

Key responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:

  • Setting up and performing immune cells-based in vitro assays (including activation, proliferation, and phenotype characterization).
  • Planning and executing in vitro studies with patient-derived organoids and allogenic/autologous immune cells
  • Executing flow cytometry staining, data collection and analysis (above 10 colors)
  • Supporting and performing multimodality experiments according to the DBT lab project.
  • Collecting and reporting data to the lab head and solving technical issues as part of a cross-functional project team.
  • Collaborating with KCL scientists within the GSK-KCL Translational Oncology Research Hub, an exclusive research collaboration between GSK and the Comprehensive Cancer Centre at KCL.



Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

  • BSc in Cell Biology/Immunology/Oncology or related, + a multidisciplinary mix of training/expertise in Oncology and immunology.
  • Proven expertise in T cell biology in tumor immune microenvironment and in immunotherapy.
  • Significant experience in cell culture techniques (immune cells and primary samples/ patient-derived organoids).
  • Extensive experience in multiple colors flow cytometry.
  • Ability to communicate with team members from different backgrounds by training/discipline, as well as senior members of the GSK stakeholders/research partner units.
  • Ability to deliver high quality, consistent results in a timely fashion with a positive can-do and result oriented attitude.



Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

  • PhD in Biology/Oncology
  • A track record of scientific publication.



Closing Date for Applications - 28th of March 2025(COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or . The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website athttps://openpaymentsdata.cms.gov/

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