Latest Isomorphic Labs Jobs

Head of Medicinal Chemistry, Drug Design, London

As Head of Medicinal Chemistry, you will lead a team of 25 chemists in London, driving the development of novel drugs using cutting-edge AI and machine learning. You will provide strategic direction, mentor team members, and collaborate closely with AI/ML scientists to accelerate drug discovery and clinical candidate nomination.

Isomorphic Labs London, United Kingdom

On-site Permanent

Senior Research Investigator, (Biologics Pharmacology), London

This role involves designing and executing pharmacology plans for large molecule therapeutics, leading in vivo and in vitro assays, and driving project milestones from early discovery to candidate selection. You will collaborate with interdisciplinary teams to integrate pharmacology data into AI-driven drug design processes.

Isomorphic Labs London, United Kingdom

On-site Permanent

Computational Drug Designer, London

As a Computational Drug Designer, you will work on cutting-edge drug discovery projects, applying AI and computational chemistry to design novel molecules. You will collaborate with interdisciplinary teams, contribute to scientific proposals, and mentor junior colleagues in a fast-paced, innovative environment.

Isomorphic Labs United Kingdom

Hybrid Permanent

Senior Security Engineer (AI Safety), London, Lausanne

This role involves securing AI-driven drug discovery systems by designing risk frameworks, protecting machine learning artifacts, and implementing security controls across AI infrastructure. The engineer will lead incident response for AI-specific threats, enforce compliance with global regulations, and develop safety mechanisms for autonomous agentic workflows and large language models in a high-stakes scientific environment.

Isomorphic Labs United Kingdom

Hybrid Permanent

Synthetic Chemistry Lead, London

As a Synthetic Chemistry Lead, you will apply your expertise to drive improvements in Isomorphic Labs' AI-powered drug discovery platform. You will collaborate with multidisciplinary teams, manage CMC projects, and represent the company externally to CROs and CDMOs.

Isomorphic Labs United Kingdom

Hybrid Permanent

Chemistry Lead (Induced Proximity), London

As a Chemistry Lead in the Induced Proximity team, you will develop and apply a state-of-the-art platform to tackle traditionally intractable drug discovery problems. You will collaborate with AI/ML and Drug Design teams to drive projects towards clinical trials, focusing on innovative molecular glue design and synthesis.

Isomorphic Labs United Kingdom

Hybrid Permanent

Bioanalytical Lead, London

This role involves leading bioanalytical strategy for a diverse portfolio of AI-designed therapeutics, including small molecules, biologics, and Antibody-Drug Conjugates. The candidate will design and validate PK, PD, and immunogenicity assays, manage global CROs, and integrate wet-lab data with AI models to accelerate preclinical development. They will also author regulatory submissions and ensure compliance across non-GLP and GLP environments.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Clinical Program Manager, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, coordinating cross-functional teams and external partners. This role involves managing timelines, budgets, risks, and vendor relationships while leveraging AI-driven insights to accelerate development. The position requires strong leadership, strategic planning, and real-time problem-solving to ensure successful clinical advancement of novel therapeutics.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

This role involves leading clinical development strategy for oncology programs, translating AI-driven insights into clinical trials, and ensuring patient safety and regulatory compliance. The Medical Director will guide drug candidates from discovery through proof-of-concept, serve as medical monitor, and collaborate with cross-functional teams and external stakeholders including regulators and key opinion leaders.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Head of Chemistry, Drug Design, Cambridge, MA

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs Cambridge, United Kingdom

Head of Computational Drug Design, Cambridge, MA

Leads the Computational Drug Design team in advancing drug discovery through AI integration, providing scientific and strategic direction from hit finding to candidate selection. Collaborates closely with AI/ML, medicinal chemistry, and biology teams to optimize workflows and drive innovation. Focuses on mentoring talent, managing external partnerships, and embedding machine learning into computational chemistry practices.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Medicinal Drug Design Lead, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Research Scientist (Applied LLMs), London

This role involves advancing drug discovery through the application of Large Language Models (LLMs) in a cutting-edge AI environment. The Research Scientist will develop and refine LLM-driven approaches for complex biological and medical challenges, collaborating across disciplines to build transformative AI models. Work includes model development, training, and deployment, with a focus on innovation in computational biology and chemistry.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Team Leader, Medicinal Drug Design, London

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs London, United Kingdom

Team / Research Leader, Computational Drug Design, London

This role involves leading the design of novel small molecule therapeutics using cutting-edge AI and computational chemistry. You will define the scientific direction, manage drug discovery programs, and mentor a high-performing team while integrating AI/ML into modern workflows.

Isomorphic Labs United Kingdom

Hybrid Permanent